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Recently, emerging evidence has identified ferroptosis, an iron-dependent regulated cell death, as a pivotal factor in driving PD pathogenesis, with close associations to key mechanisms including -syn protein aggregation, excessive oxidative stress, mitochondrial dysfunction, disturbances in iron metabolism, and activation of neuroinflammatory responses

Abbreviations: TIR, time in range

While the fermentable carbohydrates are reduced, the remaining material becomes concentrated in nutrients such as protein, amino acids, fats, minerals, and other fermentation substrates that support efficient yeast growth